Allyl estrenol
Synonyms:13-Methyl-17-prop-2-enyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol
MF:C21H32O
MW:300.48
CAS RNumber:432-60-0
EINECS:207-082-9
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Allyl estrenol (BAN/INN), also known as allyloestrenol and allyl estrenol, is a synthetic progestogen used to prevent threatened miscarriage, recurrent pregnancy loss and premature labor. In men, it has also been studied as a treatment for benign prostatic hyperplasia, with encouraging results.
It is sold under several trade names, including Gestin, Turinal,Gestrenol, Gestanin, Gestanol or Gestanon, Maintaine, Orageston, and Profar. It is currently not marketed in the United States, United Kingdom, or Canada, but as of 2011, is extensively used in Bangladesh,Japan, Russia, India, and much of Southeast Asia.
TEST ITEMS | SPECIFICATION | RESULTS |
Description | White or Almost White Crystalline Powder | white powder |
Identification | A.B. | Positive |
Assay | 97.0~103.0% | 99.3% |
Specific Rotation | +101°~+105° | +102.6° |
Loss On Drying | 1.0%max | 0.27% |
Melting Point | 153~157°C | 153.0~155.0°C |
Organic Volatile Impurities | meets the requirement. | Conforms |
Related Substances | meets the requirement. | Conforms |
Residual Solvents | meets the requirement. | Conforms |
Particle Size | 100% ≤ 20 microns | Conforms |
Conclusion | The specification conform with USP30 standard |
Allyl estrenol was used to treat 375 women with threatened pregnancies. Results show that this drug is capable of maintaining pregnancy in a large series of ambulant patients and is safe for both mother and child. Allylestrenol does not maintain pregnancy if placental dysfunction is present, however. Newborns whose mothers are treated with allylestrenol have slightly higher birth weights than controls. The possible role of allylestrenol in this process is discussed. At high doses, allylestrenol effectively stops premature labor, suggesting a selective action on the myometrium.
Allyl estrenol
25kg/Fiber Drum (35 cm* 53 cm), Double plastic bag inside;
1Kg/Aluminum foil bag, with single plastic inside, and carton outside;
And other package, or as your requirements.
Allyl estrenol
Delivery: Sea/ Air Shipping & International Express
Shipping Time: 2-3 working days after payment
Storage: Kept away from strong light and heat.
Shelf Life: 24 months
Q1: Are you manufacturer or trading company ?
A:We are trader with ISO22000,Kosher,Halal,HACCP certified over 10 years.
Q2:How can we guarantee you receive a good quality Allylestrenol?
A: Our own factory comply to GMP standard and run with strict quality control,every batch of the product must be tested and ensure the quality before shipment.
Q3: What’s the delivery and shipping ?
A:For sample,around 1-3days to be sent out upon receipt of payment by
DHL,Fedex,TNT,UPS,EMS or SF.
For small order, please expect 3-7days by DHL. FedEx,TNT,UPS EMS or SF.
For bulk order, around 2 weeks to finish production from order confirmation,will be delivered by air or sea as customer requested.
Q4: Can I get some sample to test the quality?
A: Of course you can, a 20g-30g free sample is available for you to test.
Q5: What’s the payment?
A: We accept T/T,L/C,D/A,D/P,Western Union,Paypal.
Q6:What is your package and storage?
A:25kg per paper drum with double layer poly bag inside.
Store in cool and dry place, keep away from strong light and heat.
Q7:What is your return service policy?
A: We offer a 45days guarantee on receipt of goods without any damage to packing. We will return your money if our products don’t conform to your approved quality.